📋 Research Review Process · How Studies Enter LongevLife
Research Review Process
Every study cited by LongevLife goes through a structured evaluation process. This page documents exactly how a study moves from PubMed to a LongevLife page.
Step-by-Step Review Process
1
Literature Search
PubMed search using MeSH terms for the specific topic. Filters applied: humans, English or Hebrew, published within last 10 years (last 5 years preferred). Initial search returns 50-500 results depending on topic.
Search engines: PubMed, Google Scholar, Cochrane Library
2
Title & Abstract Screen
Each result is screened by title and abstract. Studies are excluded if: animal only, review without original data, published in predatory journal, n<20, follow-up <4 weeks for supplement studies.
Typically 80-90% of initial results are excluded at this stage
3
Full Text Review
Remaining studies are read in full. Evaluated for: methodology quality (randomization, blinding, ITT analysis), sample demographics (relevant to target audience), conflict of interest disclosures, industry funding.
Industry-funded studies are included but labeled
4
Evidence Grading
Each study is assigned an evidence level (Tier 1-6) using the LongevLife Evidence Hierarchy. Key metrics extracted: effect size, sample size, p-value, confidence intervals, endpoints (surrogate vs hard).
5
DOI Verification
Every selected study must have a verifiable DOI link. The DOI is checked against the journal's official website. Studies without DOI or with broken DOIs are excluded.
100% DOI verification - no exceptions
6
Publication & Labeling
Study is published on relevant LongevLife page with: authors, journal, year, DOI link, PubMed ID, key finding summary, and evidence level label (Strong / Moderate / Preliminary).
Finding is written in our own words - no copyright infringement
500+Initial results per topic
~10%Pass abstract screen
~50%Pass full text review
100%DOI verified
Inclusion and Exclusion Criteria
✅ Inclusion Criteria
- Peer-reviewed publication
- PubMed-indexed journal
- Human participants (preferred)
- Sample size n≥20 for interventional
- DOI verifiable and active
- Published within last 15 years (10 preferred)
- Relevant to longevity or preventive health
- Clear methodology reported
- Effect size and statistical measures reported
❌ Exclusion Criteria
- Animal-only studies (for human claims)
- Preprints (not peer-reviewed)
- Predatory journal publications
- Case reports as evidence
- Expert opinion without data
- No conflict of interest disclosure
- Retracted studies
- Studies with no DOI
- Supplement company white papers
Handling Conflicting Evidence
When studies conflict - and they often do - LongevLife:
- Presents both findings transparently, labeled by evidence level
- Favors systematic reviews and meta-analyses over individual studies
- Notes when the field has "conflicting evidence" and why
- Does not selectively cite only positive findings
- Updates pages when new evidence changes the consensus
Industry-Funded Research Policy
We acknowledge that industry-funded studies exist and are sometimes the only human RCT data available. LongevLife policy:
- Industry-funded studies are included when no independent alternative exists
- They are labeled: "Note: industry-funded - interpret with appropriate caution"
- LongevLife gives additional weight to independently replicated findings
- We never exclude null findings from industry-funded studies
Research Review Process documentation last updated: June 2026 · Version 1.0